Áreas de cooperación:
Temáticas:
Persona de contacto:
Cristina Núñez González
Organismo:
Hospital Universitario Lucus Augusti
Teléfono:
0034659327038
E-mail:
Dirección:
Rúa Ulises Romero Nº1
Código Postal:
27003
Localidad:
Lugo
País:
Espanha
Tipo de apoyo solicitado:
Palabras clave:
breast cancer, luminal A, luminal B, HER2-positive, and triple negative
Descripción del proyecto:
Breast cancer (BC) is the most commonly diagnosed cancer in women worldwide. Today, even though major breast cancer subtypes have been characterized, i.e., luminal A, luminal B, HER2-positive, and triple negative, little is known about the heterogeneity of breast cancer in blood. In particular, phosphoproteins secreted or shed by cancer cells constitute a largely overlooked source of biomarker candidates that could be correlated with breast cancer subtypes and/or disease status.
Objetivos principales:
The main objective of this proposal is discovering minimally invasive protein biomarkers in blood for the early noninvasive diagnosis, classification and monitorization of different breast cancer subtypes. These new blood-based biomarkers that are highly specific could offer the potential to decrease BC morbidity as well as identify the most appropriate treatment options.